2-1-3　ⓔ文献

1. Ezzati M, Lopez AD, et al: Selected major risk factors and global and regional burden of disease. Lancet, 2002; 360: 1347–1360.

2. Lieber CS: Microsomal ethanol–oxidizing system (MEOS): the first 30 years (1968–1998)–a review. Alcohol Clin Exp Res, 1999; 23: 991–1007.

3. 横山　顕：ADH1B，ALDH2の健康障害への影響．Progress in Medicine, 2013; 33: 915–919.

4. 横山　顕：お酒を飲んでがんになる人ならない人，星和書店，2017.

5. Inoue M, Nagata C, et al: Impact of alcohol intake on total mortality and mortality from major causes in Japan: a pooled analysis of six large–scale cohort studies. J Epidemiol Community Health, 2012; 66: 448–456.

6. GBD 2016 Alcohol Collaborators: Alcohol use and burden for 195 countries and territories, 1990–2016: a systematic analysis for the Global Burden of Disease Study 2016. Lancet, 2018; 392: 1015–1035.

7. Corrao G, Bagnardi V, et al: A meta–analysis of alcohol consumption and the risk of 15 diseases. Prev Med, 2004; 38: 613–619.

8. IARC, Alcohol Consumption and Ethyl Carbamate, IARC Monographs on the Evaluation of Carinogenic Risks to Humans. IARC, 2010; 96.

9. Roerecke M, Rehm J: Irregular heavy drinking occasions and risk of ischemic heart disease: a systematic review and meta–analysis. Am J Epidemiol, 2010; 171: 633–644.

10. Saito E, Inoue M, et al: Impact of alcohol intake and drinking patterns on mortality from all causes and major causes of death in a Japanese population. J Epidemiol, 2018; 28: 140–148.

11. 真栄里仁：女性・高齢者の飲酒．Progress in Medicine, 2013; 33: 899–903.

12. Osaki Y, Kinjo A, et al: Prevalence and trends in alcohol dependence and alcohol use disorders in Japanese adults; results from periodical nationwide surveys. Alcohol Alcohol, 2016; 51: 465–473.

13. 松下幸生，松井敏史，他：アルコール依存症に併発する認知症．精神経誌，2010; 112: 774–779.

14. 福永龍繁，呂　彩子，他：アルコールと突然死－大酒家突然死症候群．医学のあゆみ，2007; 222: 648–654.